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A-Alpha Bio

A-Alpha Bio

www.aalphabio.com

A-Alpha Bio has developed a proprietary synthetic biology platform, called AlphaSeq, that enables screening against thousands of targets in a single experimental step. An all-at-once approach saves time, reduces cost, and improves success rates.

Affiliated Institution:

University of Washington

Year of company formation:

2017

Abacus Bioscience

Abacus Bioscience

abacusbioscience.com/

Abacus Bioscience is focused on developing novel and game changing immunotherapies for treating chronic infectious diseases and cancers. Abacus is developing a broad-based platform that can plug-and-play with multiple cancer or viral antigens.

Affiliated Institution:

University of Washington

Year of company formation:

2018

AbSci

AbSci

ab-sci.com/

AbSci has developed a proprietary engineered E. coli expression system, SoluPro™ that will allow for an easily optimizable and scalable production of soluble recombinant proteins. Our game-changing core technology allows proteins (including antibodies and enzymes) to be produced at a fraction of their current cost, without any corresponding loss in performance characteristics. In addition, use of the versatile SoluPro™ platform accelerates the R&D process by enabling rapid access to soluble protein for screening purposes. These therapeutic proteins and antibodies are used in cancer and hormone therapies, as well as autoimmune and blood disorder therapies.

Year of company formation:

2011

Accelerator Life Science Partners

Accelerator Life Science Partners

www.acceleratorlsp.com/

Accelerator Life Science Partners is a vehicle for disciplined and efficient investment in and management of emerging biotechnology opportunities. The company identifies, evaluates, finances and manages groundbreaking emerging life sciences opportunities.

Year of company formation:

2003

Accium Biosciences

Accium Biosciences

www.acciumbio.com/

We are a leading provider of GLP/GCP compliant accelerator mass spectrometry (AMS) services to the global pharmaceutical and life science industries. Our customers use AMS services to overcome challenges they face in drug development, including assessment of pharmacokinetics, metabolism and mass balance.

Year of company formation:

2004

Arzeda

Arzeda

www.arzeda.com/

Arzeda has the world-leading computational enzyme design technology and is changing the way people think about biocatalysis. Arzeda’s team brings more than 20 years of combined experience in the field of computational and experimental protein engineering.

Affiliated Institution:

University of Washington

Year of company formation:

2008

Cardiac Insight

Cardiac Insight

www.cardiacinsightinc.com/

Developing advanced body worn sensing and computing technologies for diagnostic testing in cardiology, respiratory and other complex disease states.

Year of company formation:

2011

Epithany

Epithany

epithany.com/

EpiThany is dedicated to the advancement of innovative therapies that can improve the lives of cancer patients. Our focus is on developing tumor vaccines that drive Th1 (tumor-eradicating) immune responses without stimulating competitive Th2 (tumor-tolerant) responses.

Affiliated Institution:

Fred Hutchinson Cancer Research Center

Year of company formation:

2015

Faraday

Faraday

faradaypharma.com/

We’re Building Something Exciting. Check Back Soon.

Affiliated Institution:

Fred Hutchinson Cancer Research Center

Year of company formation:

2013

Group14

Group14

www.group14technologies.com/

An elemental approach to better batteries: Group14 uses its unique high performance carbon engineering abilities to create cohesive silicon-carbon nanocomposites that dramatically outperform traditional carbon coated silicons. Our carbon makes any silicon work much better and when combined with our novel, low-cost nano-silicon, Group14 delivers a value proposition better than graphite.

Year of company formation:

2015

Icosavax

Icosavax

www.icosavax.com/

Icosavax is unlocking a whole class of challenging vaccine targets to improve human health. By utilizing computationally designed proteins that self-assemble into virus-like particles (VLPs), we are able to readily manufacture VLPs displaying complex antigens to target significant unmet medical needs. Our first vaccine candidate, IVX-121, is being developed to protect older adults from respiratory syncytial virus (RSV) disease.

Affiliated Institution:

University of Washington

Year of company formation:

2018

Lightspeed Microscopy

Lightspeed Microscopy

www.lightspeedbio.com/

Rapid, non-destructive slide-free 3D pathology using a unique, proprietary open-top light-sheet microscope. The unique design enables high-throughput 3D microscopy of large and/or multiple tissue specimens.

Affiliated Institution:

University of Washington

Year of company formation:

2018

Link Immunotherapeutics

Link Immunotherapeutics

www.linkimmunotherapeutics.com/

SMITE cancer.

Affiliated Institution:

Fred Hutchinson Cancer Research Center

Year of company formation:

2019

Lupa Bio

Lupa Bio

www.lupabio.com/

LUPA001: An Oral, Phase 2-Ready Biomimetic Drug for Acute and Chronic Inflammatory Diseases.

Year of company formation:

2018

Lyell Immunopharma

Lyell Immunopharma

lyell.com/

Affiliated Institution:

University of Washington

Year of company formation:

2018

MDmetrix

MDmetrix

www.mdmetrix.com/

Electronic medical records don’t allow visibility into outcomes across patients, and manual analyses are too slow and expensive. So, clinicians’ outcomes questions go unanswered, and clinical leaders are left to manage clinical and workflow performance by intuition and anecdote. Using MDmetrix’s ClinOps Control Center and AI-driven analytics, clinicians leverage real world evidence to understand outcomes, compare approaches, improve care, and monitor results–across not only patients but also teams, providers, procedures, medications, techniques, devices, and facilities.

Affiliated Institution:

Seattle Children's Research Institute

Year of company formation:

2018

Medcurity

Medcurity

medcurity.com/

The HIPPA Compliance Platform: Protect your organization and your patients’ information. With Medcurity, you can build or complement your HIPAA Privacy and Security program with the most intuitive tools and helpful guidance available.

Year of company formation:

2019

Membrion

Membrion

www.membrion.com/

Membrion has developed breakthrough Molecular Self Assembly (MSA) technology that uses readily available, non-toxic and low-cost materials to produce advanced ceramic ion exchange membranes which perform better and cost significantly less than today’s ceramic and polymer options. Membrion is currently deploying this versatile technology to the rapidly growing desalination market, helping to address the global water crisis.

Affiliated Institution:

University of Washington

Year of company formation:

2016

Modumetal

Modumetal

www.modumetal.com/

Modumetal™ is a revolutionary nanolaminated alloy that is stronger and lighter than steel and will replace conventional metals and composites in many applications, starting with military armor, and eventually in cars, planes, buildings, and other transportation and construction sectors.

Affiliated Institution:

University of Washington

Year of company formation:

2006

Neoleukin Therapeutics

Neoleukin Therapeutics

www.neoleukin.com/

Neoleukin Therapeutics uses advanced computational methods to build entirely new – de novo – therapeutic proteins to treat serious immunological disorders, including cancer and autoimmunity.

Affiliated Institution:

University of Washington

Year of company formation:

2018

Olis Robotics

Olis Robotics

www.olisrobotics.com/

Olis Robotics is a software product company specializing in remote control of any robotic system through Olis CoreOS software platform.

Through the CoreOS platform, Olis is able to provide market specific robot solutions that leverage Olis’ proprietary machine perception and machine learning technologies. The goal of Olis’ technology is to provide supervised autonomy of industrial robots to drive higher levels of operational efficiency, deliver more robust safety measures and integration of digital management frameworks of the future.

Affiliated Institution:

University of Washington

Year of company formation:

2017

One Radio

One Radio

www.oneradiocorp.com/

World’s first receiver that combines the extreme bandwidth of direct sampling (2GHz instantaneous Nyquist bandwidth) with unprecedented high dynamic range.

Affiliated Institution:

University of Washington

Year of company formation:

2016

Phase Genomics

Phase Genomics

phasegenomics.com/

Phase Genomics’ mission is to help scientists make breakthrough discoveries by providing the most complete, accurate, detailed genomes and metagenomes available from any technology.

Affiliated Institution:

University of Washington

Year of company formation:

2016

Sana Biotechnology

Sana Biotechnology

www.sana.com/

Engineered Cells As Medicines: Repairing and controlling genes in cells or replacing missing or damaged cells can solve the underlying cause of many diseases. These emerging capabilities will create novel medicines that meaningfully improve patient outcomes, and Sana aims to lead the way.

Affiliated Institution:

University of Washington

Year of company formation:

2018

Skytap

Skytap

www.skytap.com/

Skytap is the leading provider of cloud-based virtual labs that deliver 100% self-service provisioning of complex IT environments without any architectural changes.

Affiliated Institution:

University of Washington

Year of company formation:

2006

ThruWave

ThruWave

www.thruwave.com/

The ThruWave team has developed a breakthrough millimeter wave sensor for use in cube utilization,  fulfillment, warehouse inventory management, retail shelf stocking, and manufacturing.

ThruWave’s headquarters is in Seattle, Washington, has over ten employees in North America, and we are growing fast!

ThruWave’s expertise includes applied physics, electromagnetics, signal processing, and GPU computing applied to mmWave imaging and related mmWave radar system challenges.

Affiliated Institution:

University of Washington

Year of company formation:

2018

TransformativeMed

TransformativeMed

www.transformativemed.com/

Since 2007, TransformativeMed has built a reputation as a worldwide leader in Cerner EMR integration and innovation, leveraging the MPages development toolkit. Our innovative solutions have enabled more than 40 hospitals to maximize the value of their EMR investment. With Smart Health Apps from TransformativeMed, hospitals can focus on what matters most: patients, providers, and outcomes.

Affiliated Institution:

University of Washington

Year of company formation:

2012

Umoja Biopharma

Umoja Biopharma

www.umoja-biopharma.com/

Solid tumor immunotherapies fail because of antigen heterogeneity, antigen escape and a suppressive tumor micro-environment.

Umoja is developing an integrated technology platform designed to cost effectively treat any tumor, any time …

Affiliated Institution:

Seattle Children's Research Institute

Year of company formation:

2019

Wibotic

Wibotic

www.wibotic.com/

WiBotic provides the most reliable wireless power and battery intelligence solutions to charge your aerial, mobile and aquatic robot systems.

Affiliated Institution:

University of Washington

Year of company formation:

2015

EXITS: Acquisitions and IPOs

Acylin Therapeutics

Acylin is the first biotechnology company focused on developing inhibitors of cellular acylation, an enzymatic mechanism fundamental to the molecular pathology of cancer, metabolic disease and neurodegeneration.

Acquired in 2014

Alder Biopharmeceuticals

Alder’s mission is to help alleviate human suffering by generating better and safer antibody therapeutics through novel technologies. Alder uses its proprietary technologies to uniquely identify, develop, produce and market its own antibody therapeutics. As a licensing partner, Alder is also revolutionizing the way the pharmaceutical industry discovers, develops and produces antibody therapeutics.

Amnis

Amnis is developing high-throughput laboratory automation tools that use a novel molecule detection technology. The Amnis platform has both molecular and cellular-based applications in research and the clinic.

Acquired by EMD Millipore, the Life Science division of Merck KGaA, in August 2011

AnswerDash

Bellwether Bio

Bellwether Bio is a privately-held Seattle-based startup developing novel cell-free DNA-based diagnostic technologies.

Acquired by Guardant Health in April 2019

C-Sats

C-SATS is a performance management system for evaluating and improving technique in healthcare professionals rapidly, accurately and cost effectively.

Acquired by Johnson & Johnson in April 2018

Clarisonic

Pacific Bioscience Laboratories, Inc., a Washington company incorporated in 2001, is the developer of the Clarisonic™ Skin Care System, a range of devices that use sonic waves to enable users to achieve healthier, younger-looking skin.

Acquired by L’Oréal in December 2011

Corus Pharma

Corus Pharma develops pharmaceutical products that address unmet needs in infectious disease and respiratory disorders.

Acquired by Gilead Sciences, Inc. in August 2006

Decide

Decide’s e-commerce service finds the lowest prices for a vast range of consumer electronics and offers predictions on new model releases and future price changes.

Acquired by eBay in September 2013

Ekos

EKOS is developing technologies that use localized ultrasound to facilitate, enhance or control the delivery or activation of drugs at a targeted tissue site.

Acquired by BTG in May 2013

Energ2

Next Generation Energy Storage

Acquired by BASF in June 2016

Farecast

This University of Washington startup uses a combination of techniques to find patterns in the variation of airline ticket prices over time and so predict future price movements. The method may also apply to hotel rooms, rental cars and other analogous markets.

Acquired by Microsoft in April 2008

Flexminder

FlexMinder delivers Software as a Service (SaaS) that saves consumers time and money while reducing costs for TPAs, private health exchanges and health carriers. FlexMinder simplifies the consumer experience by aggregating an individual’s healthcare information from multiple sources and automating the reimbursement process for their FSA healthcare claims.

Acquired by Jellyvision in January 2017

GlobeImmune

GlobeImmune is a biopharmaceutical company developing targeted molecular immunogens (Tarmogens) for the treatment of cancer and infectious diseases.

Initial Public Offering (NASDAQ: GBIM) in July 2014

HaloSource

HaloSource, Inc. is a bioscience company that employs chitin/chitosan and N-halamine-based technologies to serve the water treatment, biomedical, home and personal care markets.

Initial Public Offering (LSE: HALO.L) in October 2010

Hyperion

Ikaria

As a fully integrated biotherapeutics company, Ikaria is positioned to help advance critical care. Leveraging a combination of highly specialized insight into human biology, clinical expertise, an intimate understanding of clinical needs and an intense level of caring allows Ikaria to achieve remarkable goals.

Acquired by Mallinckrodt in March 2015

Intelligent Ion

Intelligent Ion is developing a miniature mass spectrometer based on proprietary technologies developed at the University of Washington and California Institute of Technology/Jet Propulsion Laboratory.

Assets and intellectual property were acquired by O.I. Corp. in December 2004

Juno Therapeutics

Juno is a clinical-stage company that brings together three of the world’s leading cancer centers – Fred Hutchinson Cancer Research Center, Memorial Sloan-Kettering Cancer Center and Seattle Children’s Research Institute – in unique partnership to advance a broad pipeline of breakthrough immunotherapies.

Initial Public Offering (NASDAQ: JUNO) in December 2014

Lumera

Lumera develops electro-photonic components based on proprietary polymer materials licensed from the University of Washington.

Initial Public Offering (NasdaqNM: LMRA) in 2004

Mirador Biomedical

Mirador Biomedical is developing disposable medical devices that provide data to physicians during common medical procedures to eliminate preventable complications and make the procedures safer.

Acquired by Centurion Medical Products in October 2014

MobiSante

Mobisante, Inc. is a privately held mHealth product and services company. Their goal is to make ultrasound imaging more affordable and accessible to help health care professionals practice better medicine and to reduce costs.

Acquired by Renew Group in November 2015

Nimbic

Nimbic (formerly Physware) helps customers solve their signal integrity (SI), power integrity (PI) and EMI challenges in a variety of design areas including microprocessors, FPGAs, memory, wireless RF systems, analog systems, and high-speed serial and parallel channels.

Acquired by Mentor Graphics Corp. in May 2014

NLight

nLIGHT is a leading supplier of high-power semiconductor-based lasers for microelectronics, material processing, defense and medical applications. nLIGHT develops and manufactures fiber lasers, diode-pumped solid-state lasers and direct-diode lasers.

Initial Public Offering (Nasdaq: LASR) in April 2018

Numinous Technologies

Numinous Technologies was founded in 1996 to develop graphics and interactive video software. Among its founders are noted computer graphics scientists David Salesin of the University of Washington and Andries van Dam of Brown University.

Acquired by Microsoft in March 1999

Omeros

Omeros is a clinical-stage biopharmaceutical company committed to discovering, developing and commercializing products focused on inflammation and disorders of the central nervous system.

Initial Public Offering (NasdaqNM: OMER) in October 2009

Pathway

Pathway Medical Technologies, Inc. was founded to develop, manufacture and market medical devices for the treatment of arterial disease. The company’s initial focus is treating peripheral arterial disease (PAD) more quickly, safely and effectively than existing technologies.

Acquired by MEDRAD, Inc., an affiliate of Bayer HealthCare, in August 2011

Performant

Performant is developing leading-edge technology to optimize back-end performance of enterprise computer systems. The company’s OptiBench product suite will enable customers to completely outsource the management of their information technology system’s performance.

Acquired by Mercury Interactive in May 2003

Reality Based Learning

RBL is developing standards-based educational curriculum and assessment tools delivered through the internet. The RBL software is based on 35 years of study by Norris Haring, a founding director of the EEU Center on Human Development and Disability at the University of Washington.

Acquired by McGraw-Hill Education in April 2002

Shippable

Shippable is a cloud platform that gives developers a seamless way to add continuous integration and deployment to GitHub projects. It takes less than a minute to set up and requires no maintenance. You sign in with your GitHub credentials, add a config file, create a job, and voila – we will run your builds and tests for every code commit. Our goal is to let you focus on coding, and leave the integrating and deploying to us.

Acquired by JFrog in February 2019

Snupi Technologies

SNUPI Technologies is a sensor and services company focused on home safety, security, and loss prevention. Our customers use our devices, in connection with our monitoring service, to discover and alert themselves when a hazardous event occurs in their home. SNUPI (Sensor Network Utilizing Powerline Infrastructure) technology is an ultra-low-power, general-purpose wireless sensing platform that is easily used and maintained by leveraging the existing electrical wiring as a whole home antenna.

WallyHome technology acquired by Sears Holdings Corp. in October 2015

Uptake Medical

Uptake Medical is developing a novel, minimally invasive lung volume reduction technology for patients suffering from emphysema and other types of chronic obstructive pulmonary diseases (COPD).

Acquired by Broncus Holding Company in August 2016